On account of Catherine's Protestant sympathies, she provoked the enmity of anti-Protestant officials, who sought to turn the King against her; a warrant for her arrest was drawn up in 1545. Her book Prayers or Meditations became the first book published by an English queen under her own name.
She assumed the role of Elizabeth's guardian following the King's death, and published a second book, The Lamentations of a Sinner. Six months after Henry's death, she married her fourth and final husband, Thomas Seymour, 1st Baron Seymour of Sudeley.
Catherine had a younger brother, William, later created first Marquess of Northampton, and younger sister, Anne, later Countess of Pembroke.
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Following her first husband's demise, Catherine Parr may have spent time with the Dowager Lady Strickland, Catherine Neville, who was the widow of Catherine's cousin Sir Walter Strickland, at the Stricklands' family residence of Sizergh Castle in Westmorland (now in Cumbria).
In the summer of 1534 Catherine married secondly John Neville, 3rd Baron Latimer, her father's second cousin and a kinsman of Lady Strickland.
She was the eldest child (surviving to adulthood) of Sir Thomas Parr, lord of the manor of Kendal in Westmorland, (now Cumbria), and of the former Maud Green, daughter and co-heiress of Sir Thomas Green, lord of Greens Norton, Northamptonshire.
Sir Thomas Parr was a descendant of King Edward III, and the Parrs were a substantial northern family which included many knights.
With this marriage, Catherine became only the second woman in the Parr family to marry into the peerage.